The Study of Expanded Polytetrafluoroethylene New Material in Dural Repair

Dural defect is a common problem in neurosurgery, and the emergence of expanded polytetrafluoroethylene material provides an effective solution for rehabilitation artificial blood vessels, heart patches, other fields. However, studies on repair dura have reported occurrence adverse events cerebrospinal fluid leakage. Therefore, task improving materials cannot be delayed. In this study, new composite dural based polylactic acid-glycolic acid (expanded polytetrafluoroethylene/polylactic acid) was designed synthesized. The results vivo experiments confirmed that can fully meet requirements repairing integrity mater, providing protection intracranial structure rebuilding extracellular matrix. More importantly, greatly reduce incidence leakage inhibit inflammation. application data study New Zealand rabbit species will lay important foundation development technology.